Determination 2

Determination 2 - Isatuximab, Iberdomide, Bortezomib and Dexamethasone Induction, Followed by Risk- and Response-Adapted Consolidation and Maintenance Therapy, in Transplant-Eligible Patients With Newly Diagnosed Multiple Myeloma

Arms / Cohorts

Experimental:Arm D: Cohort 1 Maintenance Therapy Part 2, Iberdomide + Isatuximab

Not yet accepting

Other:Arm A: Induction and Screening

Not yet accepting

Active Comparator:Arm E: Cohort 2 Randomized Consolidation and Maintenance (HDM-ASCT Strategy)

Not yet accepting

Experimental:Arm B: Cohort 1 Maintenance Therapy Part 1

Not yet accepting

Experimental:Arm F: Cohort 2 Randomized Consolidation and Maintenance (Linvoseltamab Strategy)

Not yet accepting

Experimental:Arm C: Cohort 1 Maintenance Therapy Part 2, Single-Agent Iberdomide

Not yet accepting

Other:Arm G: Cohort 2 Non-randomized 3-Drug Maintenance

Not yet accepting

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